Postpartum hemorrhage (PPH) remains one of the leading causes of maternal morbidity and mortality worldwide and continues to represent a major challenge in obstetric care. Current prevention strategies rely primarily on antenatal and intrapartum risk stratification models; however, their effectiveness in real-world clinical settings remains limited.
This study aimed to evaluate the distribution of PPH cases across predefined risk categories and to explore the contribution of artificial intelligence (AI)-informed analysis in identifying hidden risk patterns using real-world clinical data.
A pilot retrospective cohort study was conducted using data from more than 3,000 deliveries in 2024 from a high-volume public maternity network in Brazil. AI-informed analytical approaches, including machine learning techniques and AI-assisted processing of unstructured clinical data, were applied to enhance pattern recognition and support epidemiological interpretation.
The overall prevalence of PPH was 6.8%. Notably, 48.1% of cases occurred in patients not classified as high risk prior to delivery, including 22.9% in the medium-risk and 25.2% in the low-risk groups. These findings demonstrate that a substantial proportion of PPH cases are not captured by traditional risk-based models.
Current risk-based prevention strategies for PPH may be insufficient in real-world clinical settings. AI-informed approaches represent a promising pathway toward more dynamic and accurate risk assessment, with potential to improve early identification and support clinical decision-making.
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